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Differential Structural Brain Changes Between Responders and Nonresponders After Physical Exercise Therapy for Chronic Nonspecific Neck Pain.

Physical exercise therapy is effective for some people with chronic nonspecific neck pain but not for others. Differences in exercise-induced pain-modulatory responses are likely driven by brain changes. We investigated […]

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Machine Learning in Spinal Cord Stimulation for Chronic Pain.

Spinal cord stimulation (SCS) is an effective treatment for chronic neuropathic pain. The success of SCS is dependent on candidate selection, response to trialing, and programming optimization. Owing to the […]

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Durable Chronic Low Back Pain Reductions to 24-Months Post-Treatment for An Accessible, 8-Week, In-Home Behavioral Skills-Based Virtual Reality Program: A Randomized Controlled Trial.

ClinicalTrials.gov NCT04415177; https://clinicaltrials.gov/ct2/show/NCT04415177.

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Aging, cell senescence, the pathogenesis and targeted therapies of intervertebral disc degeneration.

Intervertebral disc degeneration (IVDD) refers to the aging and degenerative diseases of intervertebral disc components such as nucleus pulposus, annulus fibrosus, and cartilage endplate, and is the main cause of […]

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Exploring the relationship between gratitude and depression among older adults with chronic low back pain: a sequential mediation analysis.

Gratitude has been identified as a key factor in a number of positive health-related outcomes; however, the mechanisms whereby gratitude is associated with well-being among older adults with chronic pain […]

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Transcranial magnetic stimulation for the treatment of chronic low back pain: a narrative review.

Chronic low back pain is a debilitating condition that impacts millions of individuals around the world, and also has an enormous economic impact. The impact of chronic pain does not […]

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Editorial: Insights in musculoskeletal pain: 2022.

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The Use of Virtual Reality in the Rehabilitation of Chronic Non-Specific Neck Pain: A Systematic Review and Meta-Analysis.

There has been major interest in using virtual reality (VR) as a pain-management tool. This systematic review evaluates the literature for the use of VR in the treatment of chronic […]

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Associations between gait performance and pain intensity, psychosocial factors, executive functions as well as prefrontal cortex activity in chronic low back pain patients: A cross-sectional fNIRS study.

Activities of daily living, such as walking, are impaired in chronic low back pain (CLBP) patients compared to healthy individuals. Thereby, pain intensity, psychosocial factors, cognitive functioning and prefrontal cortex […]

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Reduced Spinal Cord Gray Matter in Patients with Fibromyalgia Using Opioids Long-term.

Chronic pain involves alterations in brain gray matter volume (GMV). Moreover, opioid medications are known to reduce GMV in numerous brain regions involved in pain processing. However, no research has […]

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