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Papers of the Week


2023 Feb 01


Br J Anaesth

Corticotropin-releasing factor neurones in the paraventricular nucleus of the hypothalamus modulate isoflurane anaesthesia and its responses to acute stress in mice.

Authors

Xu Z, Hu S-W, Zhou Y, Guo Q, Wang DI, Gao Y-H, Zhao W-N, Tang H-M, Yang J-X, Yu X, Ding H-L, Cao J-L
Br J Anaesth. 2023 Feb 01.
PMID: 36737387.

Abstract

Corticotropin-releasing factor (CRF) neurones in the paraventricular nucleus (PVN) of the hypothalamus (PVN neurones) can promote wakefulness and are activated under anaesthesia. However, whether these neurones contribute to anaesthetic effects is unknown.