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Papers of the Week
Lidocaine alleviates inflammation and pruritus in atopic dermatitis by blocking different population of sensory neurons.
Abstract
Atopic dermatitis (AD) is a common chronic pruritic inflammatory skin disease that relies on neuro-immune communication while neuronal mechanism-based therapeutic attempts remain lacking. We sought to investigate the efficacy of intravenous lidocaine therapy on AD and underlying neuro-immune mechanism.