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Papers of the Week


2022 Nov


Saudi Pharm J


30


11

Design and evaluation of sustained release mucoadhesive film of sumatriptan succinate containing grafted co-polymer as the platform.

Authors

Verma S, Tonk R K, Bratty M A, Alhazmi H A, Najmi A, Kumar R, Kumar M, Taleuzzaman M, Swami G, Alam M S
Saudi Pharm J. 2022 Nov; 30(11):1527-1537.
PMID: 36465843.

Abstract

The primary goal of this research is to improve the bioavailability and efficacy of Sumatriptan succinate by incorporating it in the mucoadhesive film for the treatment of migraine. Mucoadhesive film offers an excellent substitute to deliver the drug in the systemic circulation and eliminate the chance of first-pass metabolism.