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Papers of the Week


2022 Oct


Res Pharm Sci


17


5

defatted methanolic extract ameliorated monosodium iodoacetate-induced oxidative stress andinhibited inflammation in a rat model of osteoarthritis.

Authors

Alsharif IA, Abd-Elsalam RM, Amer MS, El-Desoky AH, Abdel-Rahman RF
Res Pharm Sci. 2022 Oct; 17(5):493-507.
PMID: 36386489.

Abstract

Osteoarthritis is a degenerative joint disease without definite treatment. It is characterized by intra-articular inflammation, cartilage degeneration, subchondral bone remodeling, and joint pain. The objective of the current study was to assess the anti-osteoarthritic effect and the possible underlying mechanism of action of extract (CSE).