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Papers of the Week


2022 Nov 03


Curr Opin Anaesthesiol

Measures to prolong duration of sensory block after regional anaesthesia.

Authors

Schubert A-K, Wiesmann T, Dinges H-C
Curr Opin Anaesthesiol. 2022 Nov 03.
PMID: 36326074.

Abstract

The duration of single-injection regional anaesthesia is limited due to the inherent pharmacological properties of local anaesthetics. The ideal duration of a regional anaesthesia block lasting for the first 24 h postoperatively can be stated, while a residual analgesic effect thereafter is desirable.The aim of this review is to present current options to prolong the duration of action of single-injection peripheral regional anaesthesia in the ambulatory setting. Secondly, this review outlines and discusses the latest evidence regarding the clinical use of adjuvants and sustained-release local anaesthetics.