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Papers of the Week


2022 Jul 01


BMJ Open


12


7

Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study).

Authors

Mutubuki EN, van der Maaden T, Leung K Y, Wong A, Tulen AD, de Bruijn S, Haverman L, Knoop H, Franz E, van Hoek A J, van den Wijngaard CC
BMJ Open. 2022 Jul 01; 12(7):e062439.
PMID: 35777877.

Abstract

A substantial proportion of individuals infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), report persisting symptoms weeks and months following acute infection. Estimates on prevalence vary due to differences in study designs, populations, heterogeneity of symptoms and the way symptoms are measured. Common symptoms include fatigue, cognitive impairment and dyspnoea. However, knowledge regarding the nature and risk factors for developing persisting symptoms is still limited. Hence, in this study, we aim to determine the prevalence, severity, risk factors and impact on quality of life of persisting symptoms in the first year following acute SARS-CoV-2 infection.