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Papers of the Week


2022


Front Psychiatry


13

The Multivariate Effect of Ketamine on PTSD: Systematic Review and Meta-Analysis.

Authors

Du R, Han R, Niu K, Xu J, Zhao Z, Lu G, Shang Y
Front Psychiatry. 2022; 13:813103.
PMID: 35356723.

Abstract

Post-traumatic stress disorder (PTSD) is a serious stress-related disorder caused by traumatic experiences. However, identifying a key therapy that can be used for PTSD treatment remains difficult. Ketamine, a well-known dissociative anesthetic, is considered safe to be used in anesthesia, pain management, and antidepressant actions since 1970. At present, it is still controversial whether PTSD can be treated with ketamine. The authors performed a meta-analysis to determine whether the use of perioperative ketamine lowers the incidence of PTSD.