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Papers of the Week


2022 Mar 04


Am J Emerg Med


55

Intravenous ibuprofen versus sodium valproate in acute migraine attacks in the emergency department: A randomized clinical trial.

Authors

Dogruyol S, Gur S T A, Akbas I, Kocak M B, Kocak A O, Ceylan M, Tekyol D
Am J Emerg Med. 2022 Mar 04; 55:126-132.
PMID: 35313227.

Abstract

Sodium valproate and ibuprofen are drugs with known efficacy in the treatment of headache associated with acute migraine attacks. In this study, our aim was to compare the efficacy of these two drugs in the treatment of acute migraine attacks when administered as a single intravenous (IV) dose in the emergency department.