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Papers of the Week


2021 Dec 09


Neuroimmunomodulation

The Protective Effect of Picroside II on Isoflurane-Induced Neuronal Injury in Rats via Downregulating miR-195.

Authors

Li H, Du W, Yuan Y, Xue J, Li Q, Wang L
Neuroimmunomodulation. 2021 Dec 09:1-9.
PMID: 34883483.

Abstract

Numerous pieces of evidence demonstrated that isoflurane induces hippocampal cell injury and cognitive impairments. Picroside II has been investigated for its anti-apoptosis and antioxidant neuroprotective effects. We aimed to explore the protective effects of picroside II and the role of microRNA-195 (miR-195) on isoflurane-induced neuronal injury in rats.