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Papers of the Week


2021


Ther Adv Musculoskelet Dis


13

Efficacy and safety of celecoxib combined with JOINS in the treatment of degenerative knee osteoarthritis: study protocol of a randomized controlled trial.

Authors

Kim M S, Koh I J, Sung Y G, Park D C, Yang S C, In Y
Ther Adv Musculoskelet Dis. 2021; 13:1759720X211024025.
PMID: 34262619.

Abstract

The aim of this study will be to investigate the therapeutic effect and safety of non-steroidal anti-inflammatory drugs (NSAIDs) along with symptomatic slow-acting drugs for the treatment of osteoarthritis (SYSADOA), JOINS tablets, for degenerative knee osteoarthritis (OA) treatment and to determine the analgesic and anti-inflammatory effects of the combination therapy. In addition, we will investigate whether JOINS treatment alone after NSAID and JOINS combination treatment is effective in relieving and maintaining knee OA symptoms.