I am a
Home I AM A Search Login

Papers of the Week


Papers: 15 May 2021 - 21 May 2021


Human Studies, Pharmacology/Drug Development


2021 May 14


Psychopharmacology (Berl)

Evaluation of tradipitant, a selective NK1 antagonist, on response to oxycodone in humans.

Authors

Coe MA, Lofwall MR, Vessels V, Nuzzo PA, Walsh SL
Psychopharmacology (Berl). 2021 May 14.
PMID: 33988725.

Abstract

Preclinical studies demonstrate that the NK1 receptor is involved in opioid reinforcement and withdrawal expression. Few studies have examined the impact of treatment with NK1 antagonists on opioid response in humans.