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Papers of the Week


Papers: 20 Feb 2021 - 26 Feb 2021


Animal Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2021 Feb 20


Cephalalgia

CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache.

Authors

Kopruszinski CM, Turnes JM, Swiokla J, Weinstein TJ, Schwedt TJ, Dodick DW, Anderson T, Navratilova E, Porreca F
Cephalalgia. 2021 Feb 20:333102420981688.
PMID: 33615840.

Abstract

Determine the role of calcitonin-gene related peptide in promoting post-traumatic headache and dysregulation of central pain modulation induced by mild traumatic brain injury in mice.