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Papers of the Week


2021 Jan 06


Gut

Sofosbuvir/velpatasvir with or without low-dose ribavirin for patients with chronic hepatitis C virus infection and severe renal impairment.

Authors

Liu C-H, Chen C-Y, Su W-W, Tseng K-C, Lo C-C, Liu C-J, Chen J-J, Peng C-Y, Shih Y-L, Yang S-S, Huang C-S, Huang K-J, Chang C-Y, Tsai M-C, Kao W-Y, Fang Y-J, Chen P-Y, Su P-Y, Tseng C-W, Huang J-J, et al.
Gut. 2021 Jan 06.
PMID: 33408122.

Abstract

Data regarding the real-world effectiveness and safety of sofosbuvir/velpatasvir (SOF/VEL) with or without low-dose ribavirin (RBV) in patients with chronic hepatitis C virus (HCV) infection and severe renal impairment (RI) are limited. We evaluated the performance of SOF/VEL with or without low-dose RBV in HCV-infected patients with chronic kidney disease stage 4 or 5.