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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / IDH1-mutant primary intraventricular gliosarcoma: Case report and systematic review of a rare location and molecular profile.

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2020


Surg Neurol Int


http://www.ncbi.nlm.nih.gov/pubmed/33408906?dopt=Abstract


11

IDH1-mutant primary intraventricular gliosarcoma: Case report and systematic review of a rare location and molecular profile.

Authors

IDH1-mutant primary intraventricular gliosarcoma: Case report and systematic review of a rare location and molecular profile.
de Macedo Filho L J M, Barreto E G, Martins P L B, Filho E N S, Gerson G, de Albuquerque L A F
Surg Neurol Int. 2020; 11:372.
PMID: 33408906.

Abstract

Gliosarcoma (GS) is classified as an IDH-wild-type variant of glioblastoma (GBM). While GS is already an unusual presentation of GBM, IDH1-mutant cases are especially rare. We present an IDH1-mutant primary intraventricular GS case report and a systematic review of the molecular profile in GS correlating to the prognostic and pathogenesis of IDH1/2 mutations.
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