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Papers of the Week


Papers: 19 Dec 2020 - 25 Dec 2020


Human Studies, Pharmacology/Drug Development


2020 Dec 09


Drug Alcohol Depend

Cannabis use is associated with reduced risk of exposure to fentanyl among people on opioid agonist therapy during a community-wide overdose crisis.

Authors

Socías EM, Choi JC, Lake S, Wood E, Valleriani J, Hayashi K, Kerr T, Milloy M-J
Drug Alcohol Depend. 2020 Dec 09:108420.
PMID: 33342591.

Abstract

The ongoing opioid overdose crisis is driven largely by exposure to illicitly-manufactured fentanyl. Preliminary observational and experimental research suggests that cannabis could potentially play a role in reducing use of prescription opioids among individuals with chronic pain. However, there is limited data on the effects of cannabis on illicit opioid consumption, particularly fentanyl, especially among individuals on opioid agonist therapy (OAT). We sought to assess the longitudinal association between cannabis use and exposure to fentanyl among people on OAT.