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Papers of the Week


2020


Can J Gastroenterol Hepatol


2020

Clinical Features and Dynamics of T Cells-Related Markers in Immunocompetent Patients with Cytomegalovirus Hepatitis.

Authors

Komura T, Kagaya T, Takayama H, Yanagi M, Yoshio T, Sugimoto S, Nishino M, Orita N, Asahina Y, Nishikawa M, Kaneko S, Unoura M
Can J Gastroenterol Hepatol. 2020; 2020:8874620.
PMID: 32908853.

Abstract

Cytomegalovirus (CMV) can cause hepatitis, encephalomyelitis, and pneumonitis in immunocompromised patients. In contrast, CMV infection of immunocompetent patients can lead to the development of infectious mononucleosis and is typically self-limiting; severe complications are rare. We evaluated the pathophysiology and immunological aspects of CMV hepatitis in recently immunocompetent adult patients.