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Papers of the Week


Papers: 5 Sep 2020 - 11 Sep 2020


Human Studies

PAIN TYPE:
Migraine/Headache


2020 Sep 09


Cephalalgia

Plasma levels of vasoactive neuropeptides in pediatric patients with migraine during attack and attack-free periods.

Authors

Hanci F, Kilinc Y B, Kilinc E, Turay S, Dilek M, Kabakus N
Cephalalgia. 2020 Sep 09:333102420957588.
PMID: 32903061.

Abstract

Increasing evidence suggests that vasoactive neuropeptides such as pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38), substance P, calcitonin gene-related peptide, and vasoactive intestinal peptide are involved in the pathophysiology of migraine in adults, but their role in pediatric migraineurs remains unclear. We prospectively investigated plasma levels of these vasoactive neuropeptides in pediatric migraine patients without aura and compared the results with those of age-matched healthy controls.