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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Low-dose methadone for refractory chronic migraine accompanied by medication-overuse headache: a prospective cohort study.

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Papers: 18 Jul 2020 - 24 Jul 2020


Human Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2020 Jul 20


Neurol Sci


http://www.ncbi.nlm.nih.gov/pubmed/32691178?dopt=Abstract

Low-dose methadone for refractory chronic migraine accompanied by medication-overuse headache: a prospective cohort study.

Authors

Low-dose methadone for refractory chronic migraine accompanied by medication-overuse headache: a prospective cohort study.
Benemei S, Lupi C, De Cesaris F, Lombardi N, Bettiol A, Chiarugi A, Geppetti P, Galli V, Pracucci C, Occupati B, Mannaioni G
Neurol Sci. 2020 Jul 20.
PMID: 32691178.

Abstract

A refractory chronic migraine (RCM) accompanied by medication-overuse headache (MOH) is an extremely disabling disease. Evidence suggests that in selected patients, chronic opioids may be a valuable therapeutic option for RCM. The aim of the present study was to evaluate the effectiveness and safety of prophylaxis with low-dose methadone (LDM) in patients affected by RCM with continuous headache and MOH.
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