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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / 172 A Phase 3, Multicenter Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Olanzapine/Samidorphan in Patients with Schizophrenia.

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2020 Apr


CNS Spectr


http://www.ncbi.nlm.nih.gov/pubmed/32331006?dopt=Abstract


25


2

172 A Phase 3, Multicenter Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Olanzapine/Samidorphan in Patients with Schizophrenia.

Authors

172 A Phase 3, Multicenter Study to Assess the Long-Term Safety, Tolerability, and Efficacy of Olanzapine/Samidorphan in Patients with Schizophrenia.
Yagoda S, Graham C, Simmons A, Arevalo C, Cheng Y, McDonnell D
CNS Spectr. 2020 Apr; 25(2):309-310.
PMID: 32331006.

Abstract

Background: ALKS 3831, a combination of olanzapine and samidorphan (OLZ/SAM), is in development for the treatment of schizophrenia and is intended to provide the antipsychotic efficacy of olanzapine while mitigating olanzapine-associated weight gain. We report the safety, tolerability, and efficacy of OLZ/SAM in patients with schizophrenia in a phase 3, 52-week, open-label extension study.
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