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Papers of the Week


2019 Dec


Iran J Basic Med Sci


22


12

Analgesic effect of α-terpineol on neuropathic pain induced by chronic constriction injury in rat sciatic nerve: Involvement of spinal microglial cells and inflammatory cytokines.

Authors

Soleimani M, Sheikholeslami M A, Ghafghazi S, Pouriran R, Parvardeh S
Iran J Basic Med Sci. 2019 Dec; 22(12):1445-1451.
PMID: 32133063.

Abstract

Neuropathic pain is a prevalent and debilitating neurological disorder. Ample evidence indicates that microglial cells and inflammatory cytokines are involved in the pathogenesis of neuropathic pain. Alpha-terpineol is a monoterpenoid alcohol with inhibitory effect on inflammatory cytokines. The main purpose of this study was to evaluate the effect of α-terpineol on neuropathic pain in rats.