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Papers: 7 Sep 2019 - 13 Sep 2019
Animal Studies, Pharmacology/Drug Development
2019
J Pain Res
12
In recent years, several melatonin (MLT) receptor agonists have been approved by FDA for the treatment of sleep disorders and depression. Very few studies have shed light on their efficacy against neuropathic pain (NP). IIK-7 is an MT-2 agonist known to promote sleep. Whether IIK-7 suppresses NP has not been reported, and the signaling profile is unknown.