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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Bursting Enables GRP Neurons to Engage Spinal Itch Circuits.

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Papers: 29 Jun 2019 - 5 Jul 2019


2019 Jul 03


Neuron


http://www.ncbi.nlm.nih.gov/pubmed/31271755?dopt=Abstract


103


1

Bursting Enables GRP Neurons to Engage Spinal Itch Circuits.

Authors

Bursting Enables GRP Neurons to Engage Spinal Itch Circuits.
Petitjean H, Seguéla P, Sharif-Naeini R
Neuron. 2019 Jul 03; 103(1):5-7.
PMID: 31271755.

Abstract

In this issue of Neuron, Pagani et al. (2019) find that itch signaling occurs only when GRP neurons fire action potentials in bursts. This enables GRP release and the activation of GRPR neurons, which help carry the itch signal to the brain.
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