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Papers of the Week


2021 Apr 01


Ann Surg


273


4

Identification of Plasma Proteome Signatures Associated With Surgery Using SOMAscan.

Authors

Fong TG, Chan NY, Dillon ST, Zhou W, Tripp B, Ngo LH, Otu HH, Inouye SK, Vasunilashorn SM, Cooper Z, Xie Z, Marcantonio ER, Libermann TA
Ann Surg. 2021 Apr 01; 273(4):732-742.
PMID: 30946084.

Abstract

MINI: In this manuscript, the ability of SOMAscan technology to identify proteins differentially expressed before and after surgery in older adults was evaluated. Systems biology analyses demonstrated that inflammatory proteins and biological functions associated with the inflammatory response and immune cell regulation demonstrated the greatest changes after surgery.