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The anterior cingulate cortex (ACC), a fold of brain tissue tucked just atop the corpus callosum at the center of the brain, has become known as a hotbed of emotional […]
Learn More >Genetic mutations that produce congenital insensitivity to pain (CIP) have sparked enormous interest in the pain field in the last decade as they offer enticing clues about the pathophysiology of […]
Learn More >Women suffer from chronic pain conditions at much higher rates than men do, and they report higher pain than men. Researchers are hard at work studying the biological underpinnings of […]
Learn More >Migraine is a complex condition that causes more disability than all other neurological disorders combined. Characterized by an extreme throbbing headache, increased sensitivity to light, touch, and sound, nausea and […]
Learn More >Pain is more than a physical sensation. For many people, it extends beyond the sensory “ouch” and is associated with negative affective states, including anxiety, depression, and reduced motivation. However, […]
Learn More >Pain is a subjective experience that cannot be directly measured or quantified. This has spurred the pain field’s search for biomarkers: molecules, genes, or other biological factors that could serve […]
Learn More >Chronic pain exacts a huge toll on patients, healthcare systems, and the economy. But the way that chronic pain is typically defined—by how long it lasts—provides little information about the […]
Learn More >Editor’s note: The 17th IASP World Congress on Pain took place September 12-16, 2018, in Boston, US. At the Congress, 12 early-career pain researchers took part in the PRF Correspondents Program, a science communications training […]
Learn More >Physicians have at their disposal a battery of tests to measure heartrate, blood pressure, and temperature—objective, quantifiable indicators of disease. But no such biomarkers exist yet for chronic pain. Without […]
Learn More >When it comes to the experimental tools that researchers use to understand pain at the cellular and molecular level, dorsal root ganglion neurons from animals—and more recently from human donors—have […]
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