Cluneal neuropathy is encompassed by three distinct clinical entities. Superior, middle and inferior cluneal neuralgia make up the constellation of symptoms associated with cluneal neuropathy. Each has its own variable anatomy. Adjusted incidence rates of superior cluneal neuropathy are 1.6-11.7%. Accurate diagnosis remains challenging due to lack of standardized criteria and the aforementioned variability. Treatment may include therapeutic nerve blocks, ablative techniques, neuromodulation and surgical decompression. Gaps including those related to true incidence and work up exist. Outcomes from interventional studies are limited and mixed due to significant population heterogeneity and non-standardized treatment approaches coupled with very small sample sizes.
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