Activation of Piezo1 by intracranial hypertension induced neuronal apoptosis via activating hippo pathway.
Authors
Zeng J, Fang Z, Duan J, Zhang Z, Wang Y, Wang Y, Chen L, Wang J, Liu F
Abstract
Most of the subarachnoid hemorrhage (SAH) patients experienced the symptom of severe headache caused by intracranial hypertension. Piezo1 is a mechanosensitive ion channel protein. This study aimed to investigate the effect of Piezo1 on neurons in response to intracranial hypertension.
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