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Papers of the Week


Papers: 20 Jul 2024 - 26 Jul 2024


2024 Jul 19


J Headache Pain


39030528


25


1

Efficacy and safety of atogepant, a small molecule CGRP receptor antagonist, for the preventive treatment of migraine: a systematic review and meta-analysis.

Authors

Hou M, Luo X, He S, Yang X, Zhang Q, Jin M, Zhang P, Li Y, Bi X, Li J, Cheng C, Xue Q, Xing H, Liu Y

Abstract

Migraine is one of the most common diseases worldwide while current treatment options are not ideal. New therapeutic classes of migraine, the calcitonin gene-related peptide (CGRP) antagonists, have been developed and shown considerable effectiveness and safety. The present study aimed to systematically evaluate the efficacy and safety of atogepant, a CGRP antagonist, for migraine prophylaxis from the results of randomized controlled trials (RCTs).