I am a
Home I AM A Search Login

Papers of the Week


2022 May


FASEB J


36 Suppl 1

Immunologically active cells and infertility – Quantification of uterine Natural Killer cells in endometrial samples from patients with recurrent implantation failure.

Abstract

Despite enormous advancements of reproductive medicine, recurrent implantation failure and habitual abortion remain an ongoing issue. One of the most important aspects of successful implantation is the intricate immune regulation necessary for the acceptance of the hemiallogenic embryo. The most numerous immune cells in the decidua are uterine Natural Killer (uNK) cells. Studies suggest that changes in the uNK cells count and physiology may be responsible for the aforementioned conditions. Thus, the uNK cells testing may provide valuable insights into their pathogenesis.