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The Pain Beat (Episode 2) – Optogenetics and Chemogenetics for Pain Treatment: How Feasible Are They? How Effective Could They Be?

15 July 2020

PRF Interviews


Editor’s note: Welcome to the second episode of The Pain Beat, PRF’s new monthly podcast series! Supported by a generous grant from The MAYDAY Fund, The Pain Beat brings together the world’s leading pain investigators in order to spark dialogue and debate around important ideas in pain research. Guided by Rebecca Seal, scientific director of The Pain Beat, these podcasts feature open and spirited discussion about the hottest topics in pain and how the field moves forward from here. (Listen to Episode 1 here.)


For the second episode, The Pain Beat gathered together a group of pain researchers in Keystone, Colorado, US, where two joint Keystone Symposia, Somatosensation: From Detection to Perception and Pain: Aligning the Target, were being held from February 2-5, 2020. The podcast participants include:

  • Allan Basbaum, University of California San Francisco, US
  • Robert Gereau, Washington University School of Medicine, US
  • Yarimar Carrasquillo, National Institutes of Health, US
  • Stephani Sutherland, PRF freelancer (moderator)

The group found a quiet spot away from the hubbub of the meeting to discuss whether optogenetics and chemogenetics are feasible approaches to pain treatment and, if so, how effective they might be. The podcast also includes brief introductions to these two approaches.


Take a listen below, and consider leaving a comment on the discussion, at the bottom of the page. (The  podcast can also be accessed from Apple Podcasts here, and from Spotify here.)


                                                           Podcast participants


PRF thanks Gary Hobish for providing the audio mastering for this podcast, and Kevin Seal for creating the music.


The Pain Beat is supported by a generous grant from The MAYDAY Fund.

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