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Papers of the Week


Papers: 8 Feb 2025 - 14 Feb 2025


2025 Feb 04


Neoplasia


39908779


61

ZC3H15 suppression ameliorates bone cancer pain through inhibiting neuronal oxidative stress and microglial inflammation.

Authors

Huang LQ, Yan TX, Wang BS, Li H, Zhou NB

Abstract

Patients with advanced-stage malignancies often endure unbearable pain, partly due to the incomplete understanding of its molecular mechanisms. Zinc finger CCCH-type containing 15 (ZC3H15) is a highly conserved eukaryotic protein involved in various cellular processes, including tumor growth and inflammation. However, its impact on cancer-induced pain, especially the underlying mechanisms, remains largely unknown.