I am a
Home I AM A Search Login

Papers of the Week

Papers: 25 Feb 2023 - 3 Mar 2023

Basic Science

Genetics, Human Studies

Musculoskeletal Pain

2023 Feb 28

Lifestyle Genom


Vitamin D Metabolism Genes are Differentially Methylated in Individuals with Chronic Knee Pain.


Strath LJ, Meng L, Rani A, Huo Z, Foster TC, Fillingim RB, Cruz-Almeida Y


Recent evidence suggests that Vitamin D may interact with the epigenome and play a role in the pain experience. In order for proper functioning to occur, there must be an adequate level of Vitamin D present, made possible by enzymatic reactions that allow Vitamin D to be biologically active. The purpose of this study was to explore the epigenetic landscape of genes involved in Vitamin D metabolism in individuals with and without chronic knee pain.