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Papers of the Week
Vitamin D Metabolism Genes are Differentially Methylated in Individuals with Chronic Knee Pain.
Authors
Strath LJ, Meng L, Rani A, Huo Z, Foster TC, Fillingim RB, Cruz-Almeida YAbstract
Recent evidence suggests that Vitamin D may interact with the epigenome and play a role in the pain experience. In order for proper functioning to occur, there must be an adequate level of Vitamin D present, made possible by enzymatic reactions that allow Vitamin D to be biologically active. The purpose of this study was to explore the epigenetic landscape of genes involved in Vitamin D metabolism in individuals with and without chronic knee pain.