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Papers of the Week


Papers: 28 Sep 2024 - 4 Oct 2024


2024 Sep


CNS Neurosci Ther


39328008


30


9

Vitamin D Attenuates Neuropathic Pain via Suppression of Mitochondria-Associated Ferroptosis by Inhibiting PKCα/NOX4 Signaling Pathway.

Authors

Zhang W, Yu S, Jiao B, Zhang C, Zhang K, Liu B, Zhang X

Abstract

Neuropathic pain remains a significant unmet medical challenge due to its elusive mechanisms. Recent clinical observations suggest that vitamin D (VitD) holds promise in pain relief, yet its precise mechanism of action is still unclear. This study explores the therapeutical role and potential mechanism of VitD in spared nerve injury (SNI)-induced neuropathic pain rat model.