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Papers of the Week


Papers: 9 Sep 2023 - 15 Sep 2023

RESEARCH TYPE:
Basic Science


Genetics, Human Studies, Neurobiology

PAIN TYPE:
Migraine/Headache, Psychological/Comorbidities


2023


Front Neurosci


37694124


17

Unraveling the link: exploring the causal relationship between diabetes, multiple sclerosis, migraine, and Alzheimer’s disease through Mendelian randomization.

Authors

Xue H, Zeng L, Liu S

Abstract

Observational studies suggested that diabetes mellitus [type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM)], multiple sclerosis (MS), and migraine are associated with Alzheimer’s disease (AD). However, the causal link has not been fully elucidated. Thus, we aim to assess the causal link between T1DM, T2DM, MS, and migraine with the risk of AD using a two-sample Mendelian randomization (MR) study.