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Papers of the Week

Papers: 30 Dec 2023 - 5 Jan 2024

2024 Jan 05

J Headache Pain




Tryptophan metabolites and gut microbiota play an important role in pediatric migraine diagnosis.


Liu J, Xi K, Zhang L, Han M, Wang Q, Liu X


The pathogenesis of pediatric migraine remains unclear and presents challenges in diagnosis. Recently, growing evidence has indicated that the gut microbiota can exert modulatory functions at the gut-brain axis by directly or indirectly regulating tryptophan metabolism. Consequently, we aimed to elucidate the potential association among gut microbiota, tryptophan metabolism, and pediatric migraine while also identifying diagnostic biomarkers for pediatric migraine.