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Papers of the Week

Papers: 7 Oct 2023 - 13 Oct 2023

2023 Oct 10

J Headache Pain




Triptan non-response in specialized headache care: cross-sectional data from the DMKG Headache Registry.


Ruscheweyh R, Gossrau G, Dresler T, Freilinger T, Förderreuther S, Gaul C, Kraya T, Neeb L, Ruschil V, Straube A, Scheidt J, Jürgens TP


Triptans are effective for many migraine patients, but some do not experience adequate efficacy and tolerability. The European Headache Federation (EHF) has proposed that patients with lack of efficacy and/or tolerability of ≥ 2 triptans (‘triptan resistance’) could be considered eligible for treatment with the novel medications from the ditan and gepant groups. There is little data on the frequency of ‘triptan resistance’.