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Papers of the Week


Papers: 3 Jun 2023 - 9 Jun 2023

RESEARCH TYPE:
Basic Science


Human Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Migraine/Headache, Psychological/Comorbidities


2023 Jun


Cephalalgia


37264889


43


6

The short-term effects of CGRP monoclonal antibodies on bone turnover: A prospective cohort study.

Authors

Ray JC, Sztal-Mazer S, Baker J, Matharu MS, Hutton EJ

Abstract

Calcitonin gene-related peptide monoclonal antibodies (CGRP mAb) are an effective treatment of migraine however may have possible off-target effects. Pre-clinical studies implicate CGRP in several aspects of bone turnover and homeostasis. The clinical effect of CGRP mAb on bone turnover is not known, however.