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Papers of the Week
The role of protein kinases in diabetic neuropathic pain: an update review.
Authors
Taher MG, Mohammed MR, Al-Mahdawi MAS, Halaf NKA, Jalil AT, Alsandook TAbstract
Diabetic neuropathic pain (DNP) is a debilitating symptom of diabetic neuropathy which seriously impairs patient’s quality of life. Currently, there is no specific therapy for DNP except for duloxetine and gabapentin that show limited utility in alleviating DNP. The present review aims to discuss the central role of protein kinases in the pathogenesis of DNP and their therapeutic modulation.