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Papers of the Week


Papers: 27 May 2023 - 2 Jun 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Ex Vivo Studies, In Vitro Studies, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Arthritis, Inflammation/Inflammatory


2023 May 29


Osteoarthritis Cartilage


37257556

The recombinant Link module of human TSG-6 suppresses cartilage damage in models of osteoarthritis: a potential disease-modifying OA drug.

Authors

Drummond SP, Bartnik E, Kouvatsos N, Scott J, Dyer DP, Thomson JM, Price AJ, Anand S, Biant LC, Leeuw T, Herrmann M, Milner CM, Day AJ

Abstract

To investigate the role of endogenous TSG-6 in human osteoarthritis (OA) and assess the disease-modifying potential of a TSG-6-based biological treatment in cell, explant and animal models of OA.