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Papers of the Week


Papers: 25 Feb 2023 - 3 Mar 2023

RESEARCH TYPE:
Clinical


Human Studies, Neurobiology

PAIN TYPE:
Musculoskeletal Pain, Psychological/Comorbidities


2023


PLoS One


36854023


18


2

The modifier effect of physical activity, body mass index, and age on the association of metformin and chronic back pain: A cross-sectional analysis of 21,899 participants from the UK Biobank.

Authors

Carvalho-E-Silva AP, Ferreira PH, Harmer AR, Hartvigsen J, Ferreira ML

Abstract

There is growing evidence of the anti-inflammatory effect of the anti-diabetic drug metformin and its use to reduce pain. However, we currently lack studies investigating whether metformin is associated with a reduction in chronic back pain prevalence when considering physical activity levels, body mass index (BMI), and age.