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Papers of the Week

Papers: 9 Sep 2023 - 15 Sep 2023


Pharmacology/Drug Development

Arthritis, Inflammation/Inflammatory

2023 Sep 12

J Microencapsul


The management of osteoarthritis symptomatology through nanotechnology: a patent review.


Santos MM, Santos AM, Nascimento Júnior JAC, Andrade TA, Rajkumar G, Frank LA, Serafini MR


Osteoarthritis is considered a degenerative joint disease that is characterized by inflammation, chronic pain, and functional limitation. The increasing development of nanotechnology in drug delivery systems has provided new ideas and methods for osteoarthritis therapy. This review aimed to evaluate patents that have developed innovations, therapeutic strategies, and alternatives using nanotechnology in osteoarthritis treatment. The results show patents deposited from 2015 to November 2021 in the online databases European Patent Office and World Intellectual Property Organization. A total of 651 patents were identified for preliminary assessment and 16 were selected for full reading and discussion. The evaluated patents are focused on the intraarticular route, oral route, and topical route for osteoarthritis treatment. The intraarticular route presented a higher patent number, followed by the oral and topical routes, respectively. The development of new technologies allows us to envision a promising and positive future in osteoarthritis treatment.