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Papers of the Week


Papers: 15 Mar 2025 - 21 Mar 2025


2025 Mar 14


Curr Pain Headache Rep


40085376


29


1

The Impact of Radiation Therapy on Intrathecal Drug Delivery System Functioning and Safety.

Authors

Hao D, Lee D, Shah SS, Shekoohi S, Kaye AD

Abstract

Intrathecal drug delivery systems (IDDS) are integral to managing chronic pain and spasticity, especially in oncology patients who may also require radiation therapy (RT). Concerns regarding the potential effects of ionizing radiation on IDDS functionality have been raised, with limited but growing evidence on device resilience. This review summarizes the current literature on radiation-induced IDDS malfunctions, identifies key risk factors, and discusses mitigation strategies.