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Papers of the Week
The identification of new roles for nicotinamide mononucleotide after spinal cord injury in mice: an RNA-seq and global gene expression study.
Authors
Zhang C, Li Y, Bai F, Talifu Z, Ke H, Xu X, Li Z, Liu W, Pan Y, Gao F, Yang D, Wang X, Du H, Guo S, Gong H, Du L, Yu Y, Li JAbstract
Nicotinamide mononucleotide (NMN), an important transforming precursor of nicotinamide adenine dinucleotide (NAD+). Numerous studies have confirmed the neuroprotective effects of NMN in nervous system diseases. However, its role in spinal cord injury (SCI) and the molecular mechanisms involved have yet to be fully elucidated.