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Papers of the Week


Papers: 11 Mar 2023 - 17 Mar 2023

RESEARCH TYPE:
Clinical


Human Studies, Molecular/Cellular, Neurobiology

PAIN TYPE:
Migraine/Headache


2023 Mar 15


Neurol Sci


36920571

The effects of estradiol levels on crossmodal perception: a study on the sound induced flash illusion in healthy and menstrually related migraine individuals.

Authors

Maccora S, Bolognini N, Mannina C, Torrente A, Agnello L, Lo Sasso B, Ciaccio M, Sireci G, Brighina F

Abstract

The sound-induced flash illusion (SIFI) is a valid paradigm to study multisensorial perception. In the “fission” SIFI, multiple flashes are perceived when observing a single flash paired with two or more beeps. SIFI is largely dependent on visual and acoustic cortex excitability; in migraine, dysfunctional cortical excitability affects SIFI perception. Since estrogen peak occurring during ovulation can increase neuronal excitability, the present study aims to verify whether cortical excitability shifts linked to the menstrual cycle could influence SIFI.