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Papers of the Week


Papers: 18 Jan 2025 - 24 Jan 2025


2025 Jan 20


Headache


39834045

The “central vein sign” to differentiate multiple sclerosis from migraine.

Authors

Silvestri G, Roccatagliata L, Tazza F, Schiavi S, Coccia A, Bandettini Di Poggio M, Cellerino M, Signori A, Finocchi C, Uccelli A, Inglese M, Lapucci C

Abstract

To investigate, in two cohorts including patients with multiple sclerosis (MS) and migraine, (i) the prevalence of the “central vein sign” (CVS), (ii) the spatial distribution of positive CVS (CVS+) lesions, (iii) the threshold of CVS+ lesions able to distinguish MS from migraine with high sensitivity and specificity.