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Papers of the Week
Tetrandrine Represses Inflammation and Attenuates Osteoarthritis by Selective Inhibition of COX-2.
Authors
Gao P, Rao ZW, Li M, Sun XY, Gao QY, Shang TZ, Chen C, Zhang CLAbstract
There is a lack of effective and long-term safe drugs for the treatment of osteoarthritis (OA). Tetrandrine (Tet) has been approved and used to treat rheumatoid arthritis for several decades, but its effect on OA has not been investigated. Herein, we explored the effect of Tet on OA and its underlying mechanism.