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Papers of the Week


Papers: 20 May 2023 - 26 May 2023

RESEARCH TYPE:
Basic Science


Animal Studies, Neurobiology, Pharmacology/Drug Development

PAIN TYPE:
Neuropathic Pain


2023 May 18


Brain Res Bull


37210013

Taselisib moderates neuropathic pain through PI3K/AKT signaling pathway in a rat model of chronic constriction injury.

Authors

You HP, Xu CJ, Zhang LH, Chen ZY, Liu WF, Wang HG, He HF, Zhang LC

Abstract

Neuropathic pain is a chronic condition commonly caused by inflammation-induced disturbances or lesions of somatosensory functions in the nervous system. The aim of this study was to investigate the effects and mechanisms of Taselisib on chronic constriction injury (CCI)-induced neuropathic pain in rats.