Browse by Audience
Skip to content
Papers of the Week
Targeting TRPM channels for cerebral ischemia-reperfusion injury.
Authors
Liu DQ, Mei W, Zhou YQ, Xi HAbstract
Transient receptor potential melastatin (TRPM) channels have emerged as potential therapeutic targets for cerebral ischemia-reperfusion (I/R) injury. We highlight recent findings on the involvement of TRPM channels in oxidative stress, mitochondrial dysfunction, inflammation, and calcium overload. We also discuss the challenges and future directions in targeting TRPM channels for cerebral I/R injury.