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Papers of the Week


Papers: 4 Nov 2023 - 10 Nov 2023


2023 Nov 06


Muscle Nerve


37929655

Sustained pain and macrophage infiltration in a mouse muscle contusion model.

Authors

Cortez I, Gaffney CM, Crelli CV, Lee E, Nichols JM, Pham HV, Mehdi S, Janjic JM, Shepherd AJ

Abstract

Prior studies have emphasized the role of inflammation in the response to injury and muscle regeneration, but little emphasis has been placed on characterizing the relationship between innate inflammation, pain, and functional impairment. The aim of our study was to determine the contribution of innate immunity to prolonged pain following muscle contusion.