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Papers of the Week

Papers: 4 Nov 2023 - 10 Nov 2023

2023 Nov 06

Muscle Nerve


Sustained pain and macrophage infiltration in a mouse muscle contusion model.


Cortez I, Gaffney CM, Crelli CV, Lee E, Nichols JM, Pham HV, Mehdi S, Janjic JM, Shepherd AJ


Prior studies have emphasized the role of inflammation in the response to injury and muscle regeneration, but little emphasis has been placed on characterizing the relationship between innate inflammation, pain, and functional impairment. The aim of our study was to determine the contribution of innate immunity to prolonged pain following muscle contusion.