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Papers of the Week

Papers: 1 Apr 2023 - 7 Apr 2023

Basic Science

Animal Studies, Molecular/Cellular, Neurobiology, Pharmacology/Drug Development

2023 Apr 03

Protein Pept Lett


Study on the analgesic activity of peptide from Conus achates.


Liu X, Wang F, Yu H, Liu C, Xia J, Ma Y, Jiang H


As a peptide originally discovered from Conus achates by mass spectrometry and cDNA sequencing, Ac6.4 contains 25 amino acid residues and three disulfide bridges. Our previous study found that this peptide possesses 80% similarity to MVIIA by BLAST and that MVIIA is a potent and selective blocker of N-type voltage-sensitive calcium channels in neurons.